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Madrid to Istanbul is a 2,703 km route with a +2 hour timezone difference. Most flights have 1 stop. The shortest flight time we've seen is 5h 10m, with an average of 5h 21m.
The cheapest economy flight we're currently tracking is $179.
Airlines operating Madrid to Istanbul include Lufthansa, Lufthansa City Airlines. We're tracking trips ranging from 7 to 14 days.